Compile Data Set for Download or QSAR

Found 5 hits of ec50 data for polymerid = 50000941,50006419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Short transient receptor potential channel 3 (Homo sapiens (Human))	BDBM50239161 (CHEMBL4085233) Show SMILES CCOC(=O)N1CCC(CC1)c1cc(O)n2nc(C)c(-c3ccc(cc3)C(F)(F)F)c2n1 Show InChI InChI=1S/C22H23F3N4O3/c1-3-32-21(31)28-10-8-14(9-11-28)17-12-18(30)29-20(26-17)19(13(2)27-29)15-4-6-16(7-5-15)22(23,24)25/h4-7,12,14,30H,3,8-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc Curated by ChEMBL					Assay Description Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 m...				J Med Chem 60: 4680-4692 (2017) Article DOI: 10.1021/acs.jmedchem.7b00304 BindingDB Entry DOI: 10.7270/Q2D220RN
					More data for this Ligand-Target Pair
Short transient receptor potential channel 3 (Homo sapiens (Human))	BDBM50239160 (CHEMBL4060387) Show SMILES Cc1nn2c(O)cc(nc2c1-c1ccc(Cl)cc1)C1CCN(CC1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C26H25ClN4O3/c1-17-24(20-7-9-21(27)10-8-20)25-28-22(15-23(32)31(25)29-17)19-11-13-30(14-12-19)26(33)34-16-18-5-3-2-4-6-18/h2-10,15,19,32H,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	138	n/a	n/a	n/a	n/a
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc Curated by ChEMBL					Assay Description Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 m...				J Med Chem 60: 4680-4692 (2017) Article DOI: 10.1021/acs.jmedchem.7b00304 BindingDB Entry DOI: 10.7270/Q2D220RN
					More data for this Ligand-Target Pair
Short transient receptor potential channel 3 (Homo sapiens (Human))	BDBM50239162 (CHEMBL4060400) Show SMILES Cc1nn2c(O)cc(nc2c1-c1ccc(F)cc1)C1CCN(CC1)C(=O)OCc1ccccc1 Show InChI InChI=1S/C26H25FN4O3/c1-17-24(20-7-9-21(27)10-8-20)25-28-22(15-23(32)31(25)29-17)19-11-13-30(14-12-19)26(33)34-16-18-5-3-2-4-6-18/h2-10,15,19,32H,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	236	n/a	n/a	n/a	n/a
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc Curated by ChEMBL					Assay Description Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.				J Med Chem 60: 4680-4692 (2017) Article DOI: 10.1021/acs.jmedchem.7b00304 BindingDB Entry DOI: 10.7270/Q2D220RN
					More data for this Ligand-Target Pair
Short transient receptor potential channel 3 (Homo sapiens (Human))	BDBM50239167 (CHEMBL1496110) Show SMILES CCOC(=O)N1CCC(CC1)c1cc(O)n2nc(C)c(-c3ccc(F)cc3)c2n1 Show InChI InChI=1S/C21H23FN4O3/c1-3-29-21(28)25-10-8-14(9-11-25)17-12-18(27)26-20(23-17)19(13(2)24-26)15-4-6-16(22)7-5-15/h4-7,12,14,27H,3,8-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) and Hubei Provinc Curated by ChEMBL					Assay Description Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 m...				J Med Chem 60: 4680-4692 (2017) Article DOI: 10.1021/acs.jmedchem.7b00304 BindingDB Entry DOI: 10.7270/Q2D220RN
					More data for this Ligand-Target Pair
Short transient receptor potential channel 3 (Homo sapiens (Human))	BDBM50044849 (CHEMBL3311308) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C16H19NO3S/c1-11-9-12(2)16(13(3)10-11)17-21(18,19)15-7-5-14(20-4)6-8-15/h5-10,17H,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	<5.01E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Induction of human TRPC3 opening expressed in HEK cells by MSRII FLIPR/summary (Abse5) assay				Bioorg Med Chem Lett 24: 3100-3 (2014) Article DOI: 10.1016/j.bmcl.2014.05.012 BindingDB Entry DOI: 10.7270/Q2CC1292
					More data for this Ligand-Target Pair